Protective Effect of Magnesium Preloading on Cisplatin-induced Nephrotoxicity: A Retrospective Study

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Protective effect of magnesium preloading on cisplatin-induced nephrotoxicity: a retrospective study.

OBJECTIVE Magnesium supplementation has been reported to have a nephroprotective effect on cisplatin-induced renal dysfunction, but little evidence exists regarding the effect of magnesium preloading before cisplatin administration. We started to include magnesium preloading (8 mEq) in cisplatin-containing treatment regimens in January 2011. The aim of the present study was to evaluate whether ...

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Renal protective effect of selenium on cisplatin-induced nephrotoxicity

*Corresponding author: Ali Ghorbani M.D, Department of Nephrology, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. E-mail: [email protected] Implication for health policy/practice/research/medical education: Selenium supplementation reduces the products of oxidative stress in kidney failure patients and can be protective against cisplatin nephrotoxicity. ...

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Although cisplatin (cis-diamminedichloroplatinum II) is one of the most effective chemotherapeutic agents, its clinical use is limited because of its strong side effects on the kidneys. The aim of this study was to investigate the renoprotective effect of bovine lactoferrin (bLf) in cisplatin-induced renal failure in rats. To assess the renoprotective effect of bLf, oral bLf (300 mg/kg) was adm...

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The Effect of Hydration Therapy with and without Magnesium Sulfate on Prevention of Cisplatin-Induced Nephrotoxicity

Background: Cisplatin is an antineoplastic agent used to treat many malignancies; however, the main side effect of cisplatin is nephrotoxicity. The aim of this study was to evaluate the effect of hydration therapy with and without magnesium on prevention of cisplatin-induced nephrotoxicity. Methods: This retrospective study was performed on 46 patients with malignancy who were candidate to rec...

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ژورنال

عنوان ژورنال: Japanese Journal of Clinical Oncology

سال: 2014

ISSN: 0368-2811,1465-3621

DOI: 10.1093/jjco/hyu004